Azithromycin is a class four new drug of state-level of China, developed and manufactured by Shijiazhuang Pharmacetnjcal Group 0uyi Pharma Co ．，Ltd．in 1997．The product has been put into mass production and conforms to CP and USP specifications.

        Azithromycin can be used as the raw material for powder injection，tablets，capsules and oral suspension and so on．The presentations are 10kg and 20 kg per drum ．

       As the first 15-membered ring macrolide antibiotic，azithromycin acts mainly by blocking the transformation of bacteria into peptide and inhibiting the synthesis bacterial protein. The product has the following features：potent antibacteria1 activity，stable in acid medium，rapid absorption on oral administration．Aithromycin is widely into various tissues，with the tissue concentration 50 times higher than blood concentration．Furthermore，zithromycin has the characteristic of target cell-directed transfer in that the concentration in infectious tissues is greater than that in non-infectious tissues．Azithromycin has high bioavailability，long elimination half-life，short treatment period and few adverse reactions．Azithromycin is clinically used in upper respiratory infections, lower respiratory infections, skin and soft tissue infections and simple genital infections caused by bacteria susceptible to azithromycin.

    Tramadol hydrochloride, developed by Shijiazhuang Pharmaceutical Group Ouyi Pharma Co., Ltd. is a new drug of the second class of the state. This product has been put into mass production with the annual capacity up to 12 tons. The manufacturing process for tramadol has reached internationally advanced level. Tramadol from our company conforms to CP2000 and EP4.2 specifications, and has been filed with FDA by providing the DMF file. Tramadol can be used for production of tablets and injection. The presentation is 10kg per drum.

        Tramadol hydrochloride is a non-morphine analgesic agent, and the mechanism of action is to act on the specific receptor relating to pain in the central nervous system. Tramadol hydrochloride has the following characteristics: it has potent analgesic effect and doesn't lead to smooth muscle spasm at analgesic effective doses, it has no respiratory inhibition action and has no effects on heart rate and blood pressure. The product has mild side effects, low habituation and drug tolerance. It is clinically used for treatment of various acute and chronic pain including mild to moderate cancer pain, pain caused by bone fracture, post-operative pain and toothache. Soft tissue infections，and post-operation infections．

     Cefadroxil is a cephalosporin antibiotic developed by Shijiazhuang Pharmaceutical Group Ouyi Pharma Co., Ltd. In 1981, now the annual capacity hits 120 tons and the manufacturing process is domestically in the leading position. Cefadroxil bulk from our company complies with CP2000, USP26 and BP2000. Cefadroxil bulk can be used for production of tablets, capsules and oral solution. The presentation is 20kg per drum.

      Cefadroxil, a broad spectrum antibiotic, is the most effective antibiotic of the first generation cephalosporins. Cefadroxil is rapidly and completely absorbed without being affected by food content, it is widely distributed in various tissues and body fluid, possesses high bioavailability and has mild and transit side effects. Cefadroxil is clinically used for the treatment of respiratory infections, urinary tract infections, gynecologic and obstetric infections, ear-nose-throat infections. Soft tissue infections, and post-operation infections.

       Indomethacin is a nonsteriodal anti-inflammtory agent developed by Shijiazhuang No.1 pharmaceutical in 1970s.The current annual capacity is 300 tons and the manufacturing process is internally advance. The product from our factory meets CP,USP , BP and EP. Indomethacin bulks can be used for production of formulated drugs such as tablets, capsules and suppositories. The presentation of the product is 25kg per drum.

      Indomethacin exerts its anti-inflammatory, antipyretic and analgesic effects by inhibiting enzyme cyclooxgenase to reduce the synthesis of prostaglandin. Indomethacin restrains the form of pain nerve impulse of inflammatory tissues to inhibit inflammatory reaction, including chemotaxis of leukocytes and release of lysosomal enzyme Indomethancin effects as a antipyretic agents by acting on the temperature center in hypothalamus, which leads to vasolidation of peripheral and sweating and the increase of heat emission. Indomethacin is clinically used in arthritis of various kinds, gout, bursal synovitis, myotenositis and scapulohemeral penarthritis, fever, migraine, dysmenorrhea, post-operation and post-trauma pain.